Understanding Testosterone Replacement Therapy (TRT)

Feeling persistent fatigue, reduced libido, difficulty maintaining muscle mass, mood changes, or challenges with erectile function? These can be signs of low testosterone (hypogonadism), and testosterone replacement therapy (TRT) offers a targeted way to restore optimal levels when clinically indicated. At Revique Medical & Aesthetics, our functional wellness medical spa in Arlington, TX 76005, we specialize in root-cause, functional, and preventative medicine with expertise in men's hormone optimization and intimate wellness. Our team, with over 50 years of combined experience, creates highly customized, patient-specific treatment plans using the latest advanced technologies to address low testosterone safely and effectively, improving energy, sexual health, strength, and overall quality of life.

In this post, we'll cover what TRT is, its benefits, risks, current guidelines (including 2025 updates), and how our holistic approach stands out.

What Is Testosterone Replacement Therapy (TRT)?

TRT involves supplementing testosterone through FDA-approved forms such as injections, gels, patches, pellets, or creams to bring levels back into a healthy range. It's primarily used for men with confirmed hypogonadism, symptomatic low testosterone confirmed by blood tests (typically total testosterone below 300 ng/dL per AUA guidelines, with symptoms present).

TRT is not recommended for "normal" age-related decline without clear symptoms and low levels, nor as an anti-aging treatment alone.

Cleveland Clinic explains TRT helps improve symptoms of low testosterone in men with hypogonadism, with careful evaluation for safety. Learn more about TRT from Cleveland Clinic.

Mayo Clinic notes TRT can improve signs and symptoms in men with low T due to medical conditions. Explore testosterone therapy benefits and risks from Mayo Clinic.

Key Benefits of TRT

When appropriately prescribed for symptomatic hypogonadism, TRT offers evidence-based improvements:

  • Increased Energy and Reduced Fatigue — Many men report better daily vitality and less tiredness.

  • Improved Libido and Sexual Function — Enhanced sex drive, better erectile function, and overall sexual satisfaction.

  • Increased Muscle Mass and Strength — Helps maintain or rebuild lean muscle and reduce body fat.

  • Better Mood and Cognitive Clarity — Reduced irritability, depression, and brain fog; improved motivation and focus.

  • Bone Health Support — Helps preserve bone density and reduce fracture risk.

  • Other Potential Gains — Improved sleep quality, red blood cell production (in some cases), and sense of well-being.

Recent data, including the 2023 TRAVERSE trial and 2025 FDA label updates, confirm TRT does not increase major cardiovascular risks in appropriately selected men.

Harvard Health discusses potential benefits like improved energy, sexual function, and mood. Read more on treating low testosterone from Harvard Health.

Important Risks and Considerations

TRT is safe for many but requires monitoring. Potential risks include:

  • Erythrocytosis (elevated red blood cell count) — Can increase blood clot risk if unmanaged.

  • Prostate Effects — May stimulate existing prostate cancer (not cause new cases); regular PSA and prostate monitoring recommended.

  • Fertility Impact — Suppresses natural sperm production; important for men desiring future children.

  • Other Side Effects — Acne, sleep apnea worsening, breast tenderness, or ankle swelling in some cases.

  • No Increased CV Risk — 2025 FDA updates removed black box warnings for heart risks based on large trials.

Guidelines stress shared decision-making, baseline evaluations (PSA, hematocrit, etc.), and regular follow-up.

American Urological Association (AUA) guidelines (reviewed 2024) recommend TRT for symptomatic deficiency with levels below 300 ng/dL, with careful monitoring. View AUA Testosterone Deficiency Guideline.

Endocrine Society recommends therapy for men with symptoms and low levels to correct deficiency. Explore Endocrine Society guidelines on testosterone therapy.

The Revique Difference: Personalized, Root-Cause Care

At Revique, we don't just prescribe TRT, we identify why levels are low (e.g., obesity, sleep issues, stress, nutrient gaps) and address root causes first. Your plan may include:

  • Comprehensive testing (total/free T, SHBG, LH/FSH, estradiol, PSA, hematocrit, etc.)

  • Lifestyle optimization: Medically supervised weight loss, muscle enhancement, dietary counseling, and sleep/gut health support

  • Peptide therapy for added vitality when appropriate

  • Bioidentical testosterone options with close monitoring for safety and efficacy

  • Integration with men's sexual wellness for libido, ED, or performance concerns

We prioritize evidence-based protocols, regular labs, and shared decision-making. Flexible payment plans, financing, and membership pricing make care accessible.

Don't let low testosterone hold you back, many men experience transformative improvements with the right approach.

Ready to check your levels and discuss if TRT is right for you? Schedule a confidential consultation today at Revique Medical & Aesthetics in Arlington, TX 76005. Visit our contact page or call our office.

Reclaim strength, drive, and confidence, Revique is here to optimize your wellness!

Next
Next

Recognizing the Symptoms of Low Testosterone: What to Watch For